Aaaghhhh I hate these because I’ll often like a bunch. XD But let’s see…
DM: Mai VS Yugi’s a favorite, especially now that I’ve read through the original manga version of it. The way Mai’s disappointed that she’s not dueling him at his best because he’s thinking of dueling Pegasus, and how she tries to egg him onto getting there, was good. Also, her line about becoming stronger to overcome weakness has a lot of truth behind it.
[Honorable mention: Jonouchi VS Valon in DOMA because FUCKING ARMOR]
GX: Ryou VS Yubel!Johan. YOU KNOW THE ONE.
[Honorable mentions: Judai VS Yubel and Judai VS Darkness, the latter because of the truth behind a lot of what Judai tells everyone]
5D’s: I have two in the top spot so this is a tie! XD
Yusei VS Aki in the Fortune Cup Finals, definitely. Especially the symbolism with Stardust’s effect and Yusei trying to get Aki opened up (and the music and everything was just fskdfds;lfjsd;ljfd;slkjf [DUEL OF FORTUNE CUP! FINALS! START!! *cue Mind Games*]). And that’s tied with… Rua/Ruka/JACK VS Aporia! I mean, Rua–my son for more than 100 episodes–finally becomes a Signer? ABOUT FUCKING TIME. Also, the chills Aporia sent down my spine with “Young one, this is despair. I end my turn.” And just everything going on in that duel. Highlight of the Ark Cradle arc for me.
[Honorable mention: Yusei VS Antinomy. REST IN FUCKING PIECES SUN]
ZeXal: Have yet to see past ep.10 maybe, so I can’t really speak for it lol.
ARC-V: Yuya VS Reiji was amazing, and I look forward to a resolution.
[Honorable mentions: Yuzu VS Masumi (MCS) and Shun VS LDS Trio because 17000 ATK HOW IN THE–]
Of course, I’m sure ARC-V’ll give us more awesome duels, so that might change a bit lol. But there ya go; thanks for the ask!